Missing the Pill
This week would have been a very boring, more-of-the-same, post about Align. ™ It would have been, except that on Friday I forgot to take the day’s tablet of Align. It was my second week of taking Align using the 7-day blister packs that come in the new packaging.
Because I had, during this second week, gotten the days on the blister pack properly aligned (I couldn’t resist) with the actual days of the week, I discovered that I had missed a day on Saturday morning, when I still had a caplet marked “Friday,” in my blister pack. “Oh, well,” I thought, it won’t make a noticeable difference. Didn’t I just write a post that said so?”
The Effect of Missing the Pill
I was surprised that I did notice a difference, a distinctive sense of something missing. It’s not that anything terrible happened, or that I had more pain, or anything obvious. Just 15% more sense, for three days, that my tummy was back to struggling for equilibrium. The feeling was really very hard to put a finger on, and nothing I’d go to a doctor about, yet definitely a noticeable feeling.
That barely definable feeling did convince me that Align was actually doing something good for me, that the smooth and mellow tummy I had reported was smooth and mellow, and not imaginary. When I took Friday’s Align caplet on Saturday, I didn’t expect to notice the missed day–it wasn’t a case of a self-fulfilling prophecy.
Serving up Subjective Proof
In one kind of clinical trial, the subjects are rotated on and then off — or counterbalanced off and then on — the investigational drug to see whether the same people report different effects for placebo vs. drug.
This was my own small trial along the same lines, and I am, on admittedly small evidence, convinced of the efficacy of Align–and of the irritating quality of those Sunday through Saturday blister packs!